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Home / Proteins & Peptide

Recombinant Human METAP1 Protein (Fc Tag)

SKU : BHP10303050

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Elabscience Biotechnology Co.,Ltd

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Mfr.No.	PKSH031734
Description	A DNA sequence encoding the N-terminal domain (Met 1-Phe 272) of human METAP1 (NP_055958.2) was fused with the Fc region of human IgG1 at the N-terminus.
Alternative Names	Methionine aminopeptidase 1; MAP 1; MetAP 1; Peptidase M 1; METAP1;MAP1A;MetAP1A
Reconstitution	Please refer to the printed manual for detailed information.
Background	Processing of the N-terminal initiator methionine or formylated methionine is an essential cellular process conserved from prokaryotes to eukaryotes. The proteolytic removal of N-terminal methionine from nascent peptides is catalyzed by a family of enzymes known as methionine aminopeptidases (MetAPs) and is essential for cell growth. METAP1 and METAP2 have different substrate specificity due to the differences in both size and shape of the active sites. As a member of the M24 family of metalloproteases, METAP1 plays an important role in G(2)/M phase regulation of the cell cycle and may serve as a promising target for the discovery and development of new anticancer agents.
Reactivity	Human
Tag	N-Fc
Formulation	Lyophilized from sterile PBS, pH 7.4
Host	HEK293 Cells
Accession Number	NP_055958.2
Endotoxin Level	< 1.0 EU per ug as determined by the LAL method.
Mol Weight	57 kDa
Mw(kda)	57 kDa

Sequence Info	Met 1-Phe 272

Shipping	This product is provided as lyophilized powder which is shipped with ice packs.
Stotage Note	Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Purity	> 85 % as determined by reducing SDS-PAGE.

Product Manual	Data Sheet

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SKU	Supplier No.	Size	Your price	Quantity
BHP10303050	PKSH031734	50ug	$867		Add to Cart

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