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Home / Proteins & Peptide

Recombinant Human Interleukin-26 (IL26)

SKU : BHP10505438

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-EP873613HU
Description	May play a role in local mechanisms of mucosal immunity and seems to have a proinflammatory function. May play a role in inflammatory bowel disease. Activates STAT1 and STAT3, MAPK1/3 (ERK1/2), JUN and AKT. Induces expression of SOCS3, TNF-alpha and IL-8, secretion of IL-8 and IL-10 and surface expression of ICAM1. Decreases proliferation of intestinal epithelial cells. Is inhibited by heparin.
Alternative Names	Protein AK155 AK155
Tag	N-terminal 6xHis-B2M-tagged
Regulatory	RUO
Relevance	May play a role in local mechanisms of mucosal immunity and seems to have a proinflammatory function. May play a role in inflammatory bowel disease. Activates STAT1 and STAT3, MAPK1/3 (ERK1/2), JUN and AKT. Induces expression of SOCS3, TNF-alpha and IL-8, secretion of IL-8 and IL-10 and surface expression of ICAM1. Decreases proliferation of intestinal epithelial cells. Is inhibited by heparin.
Source	E.coli
Abbreviation	IL26
Notes	Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Protein Name	Protein AK155AK155
Expression Region	22-171aa
Mol Weight	31.6 kDa
Nature	Recombinant
Protein Description	Full Length of Mature Protein

Subcellular Location	Secreted
Uniprot	Q9NPH9, Q9NPH9
Database Links	HGNC:17119 OMIM:605679 KEGG:hsa:55801 STRING:9606.ENSP00000229134 UniGene:Hs.272350
Function	May play a role in local mechanisms of mucosal immunity and seems to have a proinflammatory function. May play a role in inflammatory bowel disease. Activates STAT1 and STAT3, MAPK1/3 (ERK1/2), JUN and AKT. Induces expression of SOCS3, TNF-alpha and IL-8, secretion of IL-8 and IL-10 and surface expression of ICAM1. Decreases proliferation of intestinal epithelial cells. Is inhibited by heparin.
Protein Families	IL-10 family
Tissue Specificity	Expressed in HVS transformed T-cells but not other T-cell lines or primary stimulated T-cells. Expressed in colonic T-cells including Th17 inflammatory T-cells; the expression is significantly increased in serum of patients with Crohn's disease (at protei
Weight	31.6 kDa

Stotage Note	Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.
Buffer	Tris-based buffer，50% glycerol
Purity	Greater than 85% as determined by SDS-PAGE.
Storage	The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Storage Buffer	Tris-based buffer,50% glycerol

Immunogen Species	Homo Sapiens (Human)

Reference	The neutrophil-mobilizing cytokine interleukin-26 in the airways of long-term tobacco smokers Karlhans Fru.et al,Clinical Science,May 21

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SKU	Supplier No.	Size	Your price	Quantity
BHP10505438	CSB-EP873613HU	1mg	$1812		Add to Cart
BHP10505438	CSB-EP873613HU	100ug	$419		Add to Cart
BHP10505438	CSB-EP873613HU	20ug	$224		Add to Cart

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