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Home / Proteins & Peptide / Recombinant Protein

Recombinant Human Insulin-like growth factor I protein (IGF1), partial (Active)

BHP10500185
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Contact us to order
Tel
+1 866.986.9598
Email
orders@biohippo.com
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Involvement In Disease Insulin-like growth factor I deficiency (IGF1 deficiency)
Subcellular Location Secreted
Uniprot P05019, P05019
Database Links

HGNC:5464

OMIM:147440

KEGG:hsa:3479

STRING:9606.ENSP00000302665

UniGene:Hs.160562
Function The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. May play a role in synapse maturation
Pathway HIF-1 signaling pathway; MAPK signaling pathway; mTOR signaling pathway; p53 signaling pathway; PI3K-Akt signaling pathway; Focal adhesion; Ras signaling pathway; Signaling pathways regulating pluripotency of stem cells; AMPK signaling; FoxO signaling pathway; Rap1 signaling pathway
Protein Families Insulin family
Research Area Cancer
Weight 7.4 kDa
Buffer 0.2 µm filtered PBS, pH 7.4,lyophilized
Purity >97% as determined by SDS-PAGE and HPLC.
Storage Buffer 0.2 μm filtered PBS, pH 7.4 ,lyophilized
Immunogen Species Homo Sapiens (Human)
SKU Supplier No. #VALUE! Your price Quantity
BHP10500185 CSB-AP002521HU   $122
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