JavaScript is currently not supported/disabled by this browser. Please enable JavaScript for full functionality.

Call Us 1 - 866 - 986 - 9598
orders@biohippo.com

Sign Up

Login
- My Order
- Return Requests
- Track my Order

Home / Proteins & Peptide

Recombinant Human IL10-RA/IL-10 R? Protein (His Tag)

SKU : BHP10304585

Contact us to order

Tel

+1 866.986.9598

Email

orders@biohippo.com

Get a Quote

Request More Infos

Elabscience Biotechnology Co.,Ltd

view supplier details

Order Now

Credit card payments now incur a 3% fee.

Contact us to order

Tel

+1 866.986.9598

Email

orders@biohippo.com

Get a Quote

Ask Merchant

Request More Infos

Sample Request

Mfr.No.	PKSH033632
Alternative Names	Interleukin-10 receptor subunit alpha; IL-10 receptor subunit alpha; IL-10R subunit alpha; IL-10RA; CDw210a; Interleukin-10 receptor subunit 1; IL-10R subunit 1; IL-10R1; CD210; IL10RA; IL-10RA
Reconstitution	Please refer to the printed manual for detailed information.
Background	Interleukin-10 Receptor alpha (IL-10Ralpha) is a transmembrane glycoprotein member of the class II cytokine receptor family. Mature human IL-10 Ralpha consists of a 214 amino acid (aa) extracellular domain (ECD), a 21 aa transmembrane segment, and a 322 aa cytoplasmic domain. Within the ECD, human IL-10 Ralpha shares 59% aa sequence identity with mouse and rat IL-10Ralpha. IL-10 Ralpha is required for mediating the effects of IL-10,a critical molecule in the control of microbial infections, allergic and autoimmune inflammation, and cancer. IL-10Ralpha is the ligand specific subunit of the IL-10 receptor complex. Noncovalent dimers of IL-10 bind to IL-10 Ralpha, resulting in the recruitment of IL-10 Rbeta. Immunosuppressive signal transduction through the IL-10 receptor complex can be inhibited by activation of TLR2, 4, or 9, enabling strengthened immune responses during infection. Polymorphisms of human IL-10 Ralpha may limit viral immune evasion by retaining full responsiveness to human IL-10 but responding weakly to the cytomegalovirus homolog of IL10.
Reactivity	Human
Tag	C-His
Description	Recombinant Human IL10-RA is produced by our Mammalian expressionsystem and the target gene encoding His22-Asn235 is expressed with a 6His tag at the C-terminus.
Formulation	Lyophilized from a 0.2 um filtered solution of PBS,pH7.4.
Host	Human Cells
Accession Number	Q13651
Endotoxin Level	< 1.0 EU per ?g as determined by the LAL method.
Mol Weight	25.2 kDa
Mw(kda)	25.2 kDa

Sequence Info	His22-Asn235

Shipping	This product is provided as lyophilized powder which is shipped with ice packs.
Stotage Note	Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Purity	> 95% as determined by reducing SDS-PAGE.

Product Manual	Data Sheet

Have you used this product?

Rate it now..!!

Login to Review

SKU	Supplier No.	Size	Your price	Quantity
BHP10304585	PKSH033632	10ug	$178		Add to Cart
BHP10304585	PKSH033632	50ug	$523		Add to Cart

ebiohippo.com provides biomedical researchers with a one-stop informatic shopping experience by transforming biotechnology products’ data into a ready-to-analyze state. We collect and unify suppliers’ data on a single platform to reduce the time of searching, uncertainty, and cost of scientific experiments.

© 2024 Biohippo. All rights reserved.