IGF2 mRNA-binding protein 2 (IGF2BP2), also known as IMP2, was found to be an HMGA2 target gene during early embryonic development. IGF2BP2 belongs to a family of RNA-binding proteins that contain six characteristics of RNA-binding modules, including two N-terminal RNA recognition motifs (RRM1 and RRM2) and four C-terminal hnRNP K-homology (KH1&KH4) domains. Its homolog, IGF2BP1/IMP1, has been shown to be essential for normal embryonic growth and development.
Alternative Names
IMP-2 ; Hepatocellular carcinoma autoantigen p62 ; IGF-II mRNA-binding protein 2 ; VICKZ family member 2 ; VICKZ2 ; Insulin-like growth factor 2 mRNA-binding protein 2 ; IGF2 mRNA-binding protein 2
Quantity
50 µg
Regulatory
RUO
Source
CHO cells
Host
Human
Endotoxin Level
<1.0 EU/μg of recombinant protein as determined by the LAL method.
Biological Activity Comment
Not determined
Weight
60.0 kDa
Description
A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers.
Format
Lyophilized PowderRecombinant Human IGF2BP2 is lyophilized from 0.2 μm filtered PBS solution, pH7.2 , 5% Trehalose.
Purity
>95% as determined by SDS-PAGE
Storage
Recombinant IGF2BP2 can be stored in working aliquots at 2° - 8°C for one month, or at -20°C to -70°C for twelve months.