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Home / Proteins & Peptide

Recombinant Human IGF2

SKU : BHP10900805

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Applied Biological Materials (abm) Inc.

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Mfr.No.	Z102345
Description	Insulin-like growth factor 2 (IGF2) is one of the mitogenic, polypeptide growth factors that belongs to the insulin family, due to its structural and functional similarity to insulin. IGF2 is mainly produced in the liver and several other tissues at certain times. IGF2 expression can be found in many tissues usually with autocrine, paracrine and endocrine functions. IGF2 mainly acts as a growth promoting hormone during gestation, and does so by binding to the tyrosine kinase type I receptor (IGF1R) as well as the IGF2 receptor cation-independent mannose 6-phosphate receptor. Mature IGF2 is highly conserved between human, bovine, and porcine species. Recombinant Human IGF2 is a single, non-glycosylated, polypeptide chain of 7.8 kDa.
Alternative Names	T3M-11-derived growth factor ; PP1446 ; Insulin-like growth factor II ; multiplication stimulating activity ; MSA ; Somatomedin-A
Quantity	10 µg
Regulatory	RUO
Source	E. coli
Host	Human
Endotoxin Level	<1.0 EU/μg of recombinant protein as determined by the LAL method
Biological Activity Comment	The ED50 as determined by dose dependent proliferation of MCF7 cells was <1ng/ml

Weight	7.8 kDa

Description	Reconstitute in sterile PBS at 100 µg/mL
Format	Lyophilized Powder Lyophilized from a 0.2 µm filtered solution in Tris and NaCl
Purity	>95% as determined by SDS-PAGE
Storage	The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity.

Immunogen Species	Homo Sapiens (Human)

MSDS	Growth Factors, Cytokines & Kinases MSDS
Other	Growth Factor and Cytokine Brochure

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SKU	Supplier No.	Size	Your price	Quantity
BHP10900805	Z102345	10µg	$64.20		Add to Cart

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