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Home / Proteins & Peptide

Recombinant Human IDH1 Protein (R132H, C-8His)

SKU : BHP10303692

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Elabscience Biotechnology Co.,Ltd

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Mfr.No.	PKSH032660
Alternative Names	Isocitrate Dehydrogenase [NADP
Reconstitution	Please refer to the printed manual for detailed information.
Background	Isocitrate Dehydrogenase {NADP} Cytoplasmic (IDH1) belongs to the isocitrate and isopropylmalate dehydrogenases family. IDH1 exists as a homodimer; binding one magnesium or manganese ion per subunit. Mutations of IDH1 have been shown to cause metaphyseal chondromatosis with aciduria and are involved in the development of glioma. IDH plays a role in the regeneration of NADPH for intraperoxisomal reductions; such as the conversion of 2; 4-dienoyl-CoAs to 3-enoyl-CoAs; as well as in peroxisomal reactions that consume 2-oxoglutarate; namely the alpha-hydroxylation of phytanic acid.
Reactivity	Human
Tag	C-8His
Description	Recombinant Human Isocitrate Dehydrogenase (NADP) Cytoplasmic is produced by our E.coli expression system and the target gene encoding Met1-Leu414(Arg132His) is expressed with a 8His tag at the C-terminus.
Formulation	Supplied as a 0.2 um filtered solution of 50mM Tris; 200mM NaCl; 10% glycerol; pH8.0.
Host	E.coli
Accession Number	O75874
Endotoxin Level	< 1.0 EU per ug as determined by the LAL method.
Mol Weight	48.1 kDa
Mw(kda)	48.1 kDa

Sequence Info	Met1-Leu414(Arg132His)

Shipping	This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.Upon receipt; store it immediately at<-20°C.
Stotage Note	Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Purity	> 95 % as determined by reducing SDS-PAGE.

Product Manual	Data Sheet

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SKU	Supplier No.	Size	Your price	Quantity
BHP10303692	PKSH032660	10ug	$223		Add to Cart
BHP10303692	PKSH032660	50ug	$593		Add to Cart

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