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Home / Proteins & Peptide

Recombinant Human HIP2/UBE2K Protein (GST Tag)

SKU : BHP10304167

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Elabscience Biotechnology Co.,Ltd

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Mfr.No.	PKSH033187
Alternative Names	Ubiquitin-Conjugating Enzyme E2 K; Huntingtin-Interacting Protein 2; HIP-2; Ubiquitin Carrier Protein; Ubiquitin-Conjugating Enzyme E2-25 kDa; Ubiquitin-Conjugating Enzyme E2(25K); Ubiquitin-Conjugating Enzyme E2-25K; Ubiquitin-Protein Ligase; UBE2K; HIP2; LIG
Reconstitution	Please refer to the printed manual for detailed information.
Background	Ubiquitin-Conjugating Enzyme E2 K (UBE2K) belongs to the E2 Ubiquitin-Conjugating Enzyme family. UBE2K is highly expressed in the brain; with highest levels found in cortex and striatum; and at lower levels in cerebellum and brainstem. UBE2K may mediate foam cell formation by the suppression of apoptosis of lipid-bearing macrophages through ubiquitination and subsequence degradation of p53/TP53. UBE2K is associated with the selective degradation of short-lived and abnormal proteins; such as the endoplasmic reticulum-associated degradation (ERAD) of misfolded lumenal proteins. In addition; UBE2K is involved in Alzheimer's disease; Huntington's disease and antigen processing through its interaction with huntingtin; and MHC-heavy chain proteins.
Reactivity	Human
Tag	N-GST
Description	Recombinant Human Ubiquitin-Conjugating Enzyme E2 K is produced by our E.coli expression system and the target gene encoding Met1-Asn200 is expressed with a GST tag at the N-terminus.
Formulation	Supplied as a 0.2 um filtered solution of 50mM HEPES; 150mM NaCl; 2mM DTT; 10% Glycerol; pH 7.5.
Host	E.coli
Accession Number	P61086
Endotoxin Level	< 1.0 EU per ug as determined by the LAL method.
Mol Weight	48.7 kDa
Mw(kda)	48.7 kDa

Sequence Info	Met 1-Asn200

Shipping	This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.Upon receipt; store it immediately at<-20°C.
Stotage Note	Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Purity	> 95 % as determined by reducing SDS-PAGE.

Product Manual	Data Sheet

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SKU	Supplier No.	Size	Your price	Quantity
BHP10304167	PKSH033187	10ug	$186		Add to Cart
BHP10304167	PKSH033187	50ug	$239		Add to Cart

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