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Home / Proteins & Peptide

Recombinant Human High affinity immunoglobulin epsilon receptor subunit alpha(FCER1A),partial

SKU : BHP10504572

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-EP008532HU
Description	Binds to the Fc region of immunoglobulins epsilon. High affinity receptor. Responsible for initiating the allergic response. Binding of allergen to receptor-bound IgE leads to cell activation and the release of mediators (such as histamine) responsible for the manifestations of allergy. The same receptor also induces the secretion of important lymphokines.
Alternative Names	c-epsilon RI-alpha, FcERI, IgE Fc receptor subunit alpha, c-epsilon RI-alpha Short name: FcERI IgE Fc receptor subunit alpha
Tag	N-terminal 6xHis-SUMO-tagged
Regulatory	RUO
Relevance	Binds to the Fc region of immunoglobulins epsilon. High affinity receptor. Responsible for initiating the allergic response. Binding of allergen to receptor-bound IgE leads to cell activation and the release of mediators (such as histamine) responsible for the manifestations of allergy. The same receptor also induces the secretion of important lymphokines.
Source	E.coli
Notes	Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Protein Name	Recommended name: High affinity immunoglobulin epsilon receptor subunit alpha; Alternative name(s): Fc-epsilon RI-alpha; Short name= FcERI; IgE Fc receptor subunit alpha
Expression Region	26-205aa
Mol Weight	37.0kDa
Nature	Recombinant
Protein Description	Partial

Subcellular Location	Cell membrane, Single-pass type I membrane protein
Uniprot	P12319, P12319
Database Links	HGNC:3609 OMIM:147140 KEGG:hsa:2205 STRING:9606.ENSP00000357097 UniGene:Hs.897
Function	Binds to the Fc region of immunoglobulins epsilon. High affinity receptor. Responsible for initiating the allergic response. Binding of allergen to receptor-bound IgE leads to cell activation and the release of mediators (such as histamine) responsible for the manifestations of allergy. The same receptor also induces the secretion of important lymphokines.
Pathway	Fc epsilon RI signaling pathway; Oxidative Phosphorylation; Phospholipase D signaling pathway; Sphingolipid signaling pathway
Research Area	Immunology
Weight	37 kDa

Stotage Note	Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.
Buffer	Tris-based buffer，50% glycerol
Purity	Greater than 90% as determined by SDS-PAGE.
Storage	The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Storage Buffer	Tris-based buffer,50% glycerol

Immunogen Species	Homo Sapiens (Human)

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SKU	Supplier No.	Size	Your price	Quantity
BHP10504572	CSB-EP008532HU	1mg	$1812		Add to Cart
BHP10504572	CSB-EP008532HU	100ug	$419		Add to Cart
BHP10504572	CSB-EP008532HU	20ug	$224		Add to Cart

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