Fibrinogen-like protein 1; FGL1; HP-041; Hepassocin; HFREP-1; LFIRE-1
Background
Fibrinogen-like protein 1(FGL1) is also known as HP-041, Hepassocin, HFREP-1, LFIRE-1, is a liver-specific secreted protein belonging to the fibronogen superfamily, whose members share a fibrinogen domain at their C-termini. It is secreted by the liver and functions as a mitogen for hepatocytes. Hepassocin may play a role in the development of hepatocellular carcinomas. Hepassocin is a disulfide-linked homodimeric protein with a C-terminal fibrinogen domain. It is reported that it is a major immune inhibitory ligand of LAG-3 .
Description
Recombinant Human Fibrinogen-like Protein 1 is produced by our Mammalian expression system and the target gene encoding Leu23-Ile312 is expressed with a 6His tag at the C-terminus.
Molecular Weight
35 KDa
Accession Number
Q08830
Endotoxin Level
Less than 0.1 ng/ug (1 EU/ug) as determined by LAL test.
Shipping
The product is shipped on dry ice/polar packs. Upon receipt, store it immediately at the temperature listed below.
Purity
Greater than 90%
Storage
Store at <=-70°C, stable for 6 months after receipt. Store at <=-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.