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Home / Proteins & Peptide

Recombinant Human FGFR4 (N-GST tag)

SKU : BHP10900590

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Applied Biological Materials (abm) Inc.

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Mfr.No.	Z500144
Description	FGFR4 is a member of the fibroblast growth factor receptor family which play a role in mitogenesis and differentiation . FGFR4 preferentially binds acidic fibroblast growth factor and is overexpressed in gynecological tumor samples, suggesting a role in breast and ovarian tumorigenesis. FGFR4 gene expression is up-regulated in doxorubicin-treated, apoptosis-resistant cancer cell clones . Ectopic expression of FGFR4 in cancer cells leads to reduced apoptosis sensitivity on treatment with doxorubicin or cyclophosphamide, whereas knockdown of endogenous FGFR4 expression in breast cancer cell lines has the opposite effect.
Alternative Names	TKF ; JTK2 ; CD334 ; MGC20292
Tag	N-GST tag
Quantity	10 µg
Regulatory	RUO
Source	Insect cells
Host	Human
Biological Activity Comment	The specific activity of FGFR4 was determined to be76 nmol /min/mg as per activity assay protocol.

Weight	65.0 kDa

Format	Liquid 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
Purity	70% - 90%
Storage	Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

Immunogen Species	Homo Sapiens (Human)

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SKU	Supplier No.	Size	Your price	Quantity
BHP10900590	Z500144	10µg	$361.11		Add to Cart

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