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Home / Proteins & Peptide

Recombinant Human Cytoplasmic dynein 2 light intermediate chain 1(DYNC2LI1)

SKU : BHP10504719

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-EP844722HUe0
Description	May function as a motor for intraflagellar retrograde transport. Functions in cilia biogenesis
Tag	N-terminal GST-tagged
Regulatory	RUO
Relevance	May function as a motor for intraflagellar retrograde transport. Functions in cilia biogenesis
Source	E.coli
Notes	Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Expression Region	1-352aa
Mol Weight	66.8kDa
Nature	Recombinant
Protein Description	Full Length of Isoform 2

Involvement In Disease	Short-rib thoracic dysplasia 15 with polydactyly (SRTD15)
Subcellular Location	Cytoplasm, Cell projection, cilium, Cytoplasm, cytoskeleton, cilium basal body, Cytoplasm, cytoskeleton, cilium axoneme, Cytoplasm, cytoskeleton, microtubule organizing center, centrosome
Uniprot	Q8TCX1, Q8TCX1
Database Links	HGNC:24595 OMIM:617083 KEGG:hsa:51626 STRING:9606.ENSP00000260605 UniGene:Hs.371597
Function	Required for correct intraflagellar transport (IFT), the bi-directional movement of particles required for the assembly, maintenance and functioning of primary cilia. Involved in the regulation of ciliary length.
Protein Families	Dynein light intermediate chain family
Research Area	Signal Transduction
Tissue Specificity	Expressed in bone, brain, kidney, and cartilage (PubMed:26077881, PubMed:26130459). Lower expression in heart, liver, lung, placenta and thymus (PubMed:26077881).
Weight	66.8 kDa

Stotage Note	Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.
Buffer	Tris-based buffer，50% glycerol
Purity	Greater than 90% as determined by SDS-PAGE.
Storage	The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Storage Buffer	Tris-based buffer,50% glycerol

Immunogen Species	Homo Sapiens (Human)

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SKU	Supplier No.	Size	Your price	Quantity
BHP10504719	CSB-EP844722HUe0	1mg	$1812		Add to Cart
BHP10504719	CSB-EP844722HUe0	100ug	$419		Add to Cart
BHP10504719	CSB-EP844722HUe0	20ug	$224		Add to Cart

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