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Home / Proteins & Peptide

Recombinant Human CXCR4 (C28A) Protein (His Tag)

SKU : BHP10305021

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Elabscience Biotechnology Co.,Ltd

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Mfr.No.	PKSH500022
Description	A DNA sequence encoding the human CXCR4 (C28A) (1M-38K) was expressed with a GST tag at the N-terminus.
Alternative Names	C-X-C chemokine receptor type 4, CD184, FB22, Fusin, HM89, HSY3RR, LAP3, LCR1, NPYR, SDF 1 receptor, WHIM
Reconstitution	Please refer to the printed manual for detailed information.
Background	Receptor for the C-X-C chemokine CXCL12/SDF-1 that transduces a signal by increasing intracellular calcium ions levels and enhancing MAPK1/MAPK3 activation. Acts as a receptor for extracellular ubiquitin; leading to enhance intracellular calcium ions and reduce cellular cAMP levels. Involved in haematopoiesis and in cardiac ventricular septum formation. Plays also an essential role in vascularization of the gastrointestinal tract, probably by regulating vascular branching and/or remodeling processes in endothelial cells. Could be involved in cerebellar development. In the CNS, could mediate hippocampal-neuron survival. Acts as a coreceptor (CD4 being the primary receptor) for HIV-1 X4 isolates and as a primary receptor for some HIV-2 isolates. Promotes Env-mediated fusion of the virus.
Reactivity	Human
Tag	N-GST
Formulation	Lyophilized from sterile potassium phosphate, pH 7.4
Host	E.coli
Accession Number	P61073
Endotoxin Level	Not tested.
Mol Weight	31.2kDa
Mw(kda)	31.2kDa

Sequence Info	1M-38K

Shipping	This product is provided as liquid which is shipped with ice packs.
Stotage Note	Samples are stable for up to twelve months from date of receipt at -70°C.Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Purity	>95 % as determined by reducing SDS-PAGE.

Product Manual	Data Sheet

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SKU	Supplier No.	Size	Your price	Quantity
BHP10305021	PKSH500022	20ug	$199		Add to Cart
BHP10305021	PKSH500022	100ug	$399		Add to Cart

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