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Home / Proteins & Peptide

Recombinant Human Complement Component C8 Gamma Chain/C8G Protein (His Tag)

SKU : BHP10303347

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Elabscience Biotechnology Co.,Ltd

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Mfr.No.	PKSH032271
Alternative Names	Complement component C8 gamma chain;C8G
Reconstitution	Please refer to the printed manual for detailed information.
Background	Complement component C8 is a constituent of the membrane attack complex, C8 alpha, C8 beta and C8G. C8G is a secreted protein and comsists a disulfide-linked C8 alpha-gamma heterodimer and a non-covalently associated C8 beta chain. C8 alpha and C8 beta play an important role in complement-mediated bacterial killing together.C8 is involved in the formation of Membrane Attack Complex on bacterial cell membranes. C8 binds to the C5B-7 complex, forming the C5B-8 complex. C5-B8 binds C9 and acts as a catalyst in the polymerization of C9. The gamma subunit seems to be able to bind retinol. Patients lacking C8 are susceptible to certain bacterial infections.
Reactivity	Human
Tag	N-6His
Description	Recombinant Human Complement component C8 gamma chain is produced by our E.coli expression system and the target gene encoding Gln21-Arg202 is expressed with a 6His tag at the N-terminus.
Formulation	Supplied as a 0.2 um filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
Host	E.coli
Accession Number	P07360
Endotoxin Level	< 1.0 EU per ug as determined by the LAL method.
Mol Weight	22.6 kDa
Mw(kda)	22.6 kDa

Sequence Info	Gln21-Arg202

Shipping	This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.Upon receipt, store it immediately at<-20°C.
Stotage Note	Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Purity	> 90 % as determined by reducing SDS-PAGE.

Product Manual	Data Sheet

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SKU	Supplier No.	Size	Your price	Quantity
BHP10303347	PKSH032271	10ug	$275		Add to Cart
BHP10303347	PKSH032271	50ug	$525		Add to Cart

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