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Home / Proteins & Peptide / Recombinant Protein

Recombinant Human Carbonic anhydrase 2 (CA2) (Active)

SKU : BHP10512422

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-MP004370HU(A4)
Alternative Names	Carbonic anhydrase 2; EC:4.2.1.1 ; Carbonate dehydratase II; Carbonic anhydrase C (CAC); Carbonic anhydrase II (CA-II); Cyanamide hydratase CA2
Reconstitution	We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Tag	C-terminal 10xHis-tagged
Molecular Weight	30.7 kDa
Relevance	Catalyzes the reversible hydration of carbon dioxide. Can also hydrate cyanamide to urea. Stimulates the chloride-bicarbonate exchange activity of SLC26A6. Essential for bone resorption and osteoclast differentiation. Involved in the regulation of fluid secretion into the anterior chamber of the eye. Contributes to intracellular pH regulation in the duodenal upper villous epithelium during proton-coupled peptide absorption.
Source	Mammalian cell
Form	Lyophilized powder
Notes	Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Expression Region	1-260aa
Lead Time	3-7 business days
Protein Length	Full Length

Uniprot	P00918
Gene Name	CA2
Research Area	Signal Transduction
Sequence	MSHHWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASFK

Buffer	Lyophilized from a 0.2 um filtered 20 mM Tris-HCl,0.5 M NaCl,6% Trehalose, pH 8.0.
Purity	Greater than 95% as determined by SDS-PAGE.
Storage	The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Reference	Regulation of the human NBC3 Na+/HCO3- cotransporter by carbonic anhydrase II and PKA. Loiselle F.B., Morgan P.E., Alvarez B.V., Casey J.R. Am. J. Physiol. 286:C1423-C1433 (2004)

Product Manual	MSDS

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SKU	Supplier No.	Size	Your price	Quantity
BHP10512422	CSB-MP004370HU(A4)	20ug	$98		Add to Cart

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