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Home / Proteins & Peptide

Recombinant Human BRCA2 Protein (His Tag)

SKU : BHP10305010

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Elabscience Biotechnology Co.,Ltd

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Mfr.No.	PKSH500011
Description	A DNA sequence encoding the Human BRCA2 (P51587-1) (Thr2350-Val2545) was expressed with a polyhistidine tag at the N-terminus.
Alternative Names	BRCA 2,BRCA1/BRCA2 containing complex subunit 2,Brca2,BRCA2,DNA repair associated,BRCA2,BRCC 2,BRCC2,Breast and ovarian cancer susceptibility gene early onset,breast and ovarian cancer susceptibility protein 2,Breast cancer 2 early onset,Breast Cancer 2 tumor suppressor,Breast cancer susceptibility protein BRCA2,Breast cancer type 2 susceptibility protein,BROVCA2,FACD,FAD 1,FAD,FAD1,FANCB,FANCD 1,FANCD,FANCD1,FANCD1 gene,Fanconi anemia complementation group D1,Fanconi anemia group D1 protein,GLM3,mutant BRCA2,OTTHUMP00000018803,OTTHUMP00000042401,PNCA2,XRCC11
Reconstitution	Please refer to the printed manual for detailed information.
Background	Inherited mutations in BRCA1 and this gene, BRCA2, confer increased lifetime risk of developing breast or ovarian cancer. Both BRCA1 and BRCA2 are involved in maintenance of genome stability, specifically the homologous recombination pathway for double-strand DNA repair. The BRCA2 protein contains several copies of a 70 aa motif called the BRC motif, and these motifs mediate binding to the RAD51 recombinase which functions in DNA repair. BRCA2 is considered a tumor suppressor gene, as tumors with BRCA2 mutations generally exhibit loss of heterozygosity (LOH) of the wild-type allele.
Reactivity	Human
Tag	N-His
Formulation	Lyophilized from sterile PBS, pH 7.4
Host	E.coli
Accession Number	P51587-1
Endotoxin Level	No data available.
Bioactivity	Immunogen(E-AB-40288)
Mol Weight	22.1kDa
Mw(kda)	22.1kDa

Sequence Info	Thr2350-Val2545

Shipping	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Stotage Note	Samples are stable for up to twelve months from date of receipt at -70°C.Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Purity	>85 % as determined by reducing SDS-PAGE.

Product Manual	Data Sheet

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SKU	Supplier No.	Size	Your price	Quantity
BHP10305010	PKSH500011	20ug	$99		Add to Cart
BHP10305010	PKSH500011	100ug	-		Add to Cart

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