Recombinant Human BCMA (C-Fc)

Mfr.No.	EPT174
Description	Recombinant Human B-cell Maturation Protein is produced by our Mammalian expression system and the target gene encoding Met1-Ala54 is expressed with a Fc tag at the C-terminus.
Alternative Names	Tumor necrosis factor receptor superfamily member 17;TNFRSF17;B-cell maturation protein;CD269
Background	B cell maturation protein (BCMA) is a type III membrane protein which belongs to the TNF receptor superfamily (TNFRSF17). BCMA contains one extracellular cysteine rich domain, as well as TACI. Human BCMA is a 184 amino acid (aa) protein consisting of a 54 aa extracellular domain, a 23 aa transmembrane domain, and a 107 aa intracellular domain. Mouse and human BCMA share 62% amino acid identity. BCMA is mainly expressed in immune organs and mature B cell lines. BCMA appears to be localized to the Golgi compartment. BCMA may play an important role in B cell development, function and regulation.
Biological Activity	Loaded Mouse BAFF-mFc(Cat#C06U) on AMC Biosensor, can bind Human BCMA-Fc(Cat#CS79) with an affinity constant of 0.44 nM as determined in BLI assay.
Molecular Weight	32.8 KDa
Accession Number	Q02223
Endotoxin Level	Less than 0.1 ng/ug (1 EU/ug) as determined by LAL test.
Notes	Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100ug/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Shipping	The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below.
Purity	Greater than 95%
Storage	Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

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SKU	Supplier No.	Size	Your price	Quantity
BHP15200174	EPT174	50ug	$409		Add to Cart