AMPK is a heterotrimer protein kinase consisting of an a catalytic subunit, and non-catalytic ß and ? subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status . In response to cellular metabolic stresses, AMPK is activated and phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating biosynthesis of fatty acid and cholesterol .
Alternative Names
MGC33776 ; MGC57364 ; Subunit A1: PRKAA1
Tag
C-His tag
Quantity
10 µg
Regulatory
RUO
Source
Insect cells
Host
Human
Biological Activity Comment
The specific activity of AMPK was determined to be 737 nmol /min/mg as per activity assay protocol.
Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Immunogen Species
Homo Sapiens (Human)
Reviews of Recombinant Human AMPK (A1/B1/G1) (C-His tag)