Capsid protein p24;Human immunodeficiency virus 1;Human immunodeficiency virus type 1 p24
Background
The HIV1 p24 protein performs highly complex orchestrated tasks during the assembly,budding maturation and infection stages of the viral replication cycle. During viral assembly,the proteins form membrane associations and self-associations that ultimately result in budding of an immature virion from the infected cell. Gag p24, the major capsid protein of the HIV-1 virion, has been used in clinical trials as one of the components of the HIV-1 vaccine because of the high degree of sequence conservation between different isolates. Recombinant HIV1-p24 protein, fused to His-tag at C-terminus, was expressed in E.coli and purified by using conventional chromatography.
Reactivity
HIV
Tag
C-6His
Description
Recombinant HIV p24 protein is produced by E.coli expression system and the target gene encoding Met142-Gly355 is expressed with a 6His tag at the C-terminus.
Formulation
Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual.
Host
E.coli
Accession Number
P12493
Endotoxin Level
Please contact us for more information.
Mol Weight
24.6kDa
Mw(kda)
24.6kDa
Sequence Info
Met142-Gly355
Shipping
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.Upon receipt; store it immediately at<-20°C.
Stotage Note
Store at < -20°C, stable for 6 months after receipt. Please minimize freeze-thaw cycles.