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Home / Proteins & Peptide

Recombinant FGF-10, His, Human

SKU : BHP11300024

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Mfr.No.	BK0032‐10μg
Description	Fibroblast Growth Factor-10 (FGF-10) is a mitogen mainly produced by mesenchymal stem cells in lung. FGF-10 belongs to the heparin binding FGF family, and is also known as Keratinocyte Growth Factor-2 (KGF-2). It shares the homolog and receptor FGFR2-IIIb with KGF. However, unlike KGF which induces the proliferation and differentiation of various epithelial cells, FGF-10 is an essential factor for the budding and branching morphogenesis during the multi-organ development via the instructive mesenchymal-epithelial interactions. FGF-10 is crucial for lung and limb development, and is regulated by Shh during early development. Recombinant human Fibroblast Growth Factor-10 (rhFGF-10) with N-terminal His-tag produced in E. coli is a single non-glycosylated polypeptide chain containing 187 amino acids. A fully biologically active molecule, rhFGF-10 has a molecular mass of 21.4 kDa analyzed by reducing SDS-PAGE and is obtained by proprietary chromatographic techniques at GenScript.
Alternative Names	Fibroblast Growth Factor-10 ; FGFA ; Keratinocyte growth factor-2
Tag	His
Regulatory	RUO
Source	Escherichia coli.
Host	Human
Endotoxin Level	< 0.2 EU/μg, determined by LAL method.
Biological Activity Comment	ED50 < 20 ng/mL, measured by a cell proliferation assay using 4MBr-5 cells, corresponding to a specific activity of > 5.0× 10ˆ4 units/mg.
Nature	Recombinant

Weight	21.4 kDa, observed by reducing SDS-PAGE.
Antigen	FGF-10

Description	Reconstituted in ddH2O at 100 μg/mL.
Format	Lyophilized after extensive dialysis against PBS. Sterile Filtered White lyophilized (freeze-dried) powder.
Purity	> 95% by SDS-PAGE analysis.
Storage	Lyophilized recombinant human Fibroblast Growth Factor-10 (rhFGF-10) remains stable up to 6 months at -80°C from date of receipt. Upon reconstitution, rhFGF-10 should be stable up to 2 weeks at 4°C or up to 3 months at -20°C.

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SKU	Supplier No.	Size	Your price	Quantity
BHP11300024	BK0032‐10μg	10μg	$188.67		Add to Cart
BHP11300024	BK0032‐10μg	1mg	$3086.67		Add to Cart
BHP11300024	BK0032‐10μg	50μg	$290		Add to Cart

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