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Home / Proteins & Peptide

Recombinant Cynomolgus 4-1BB (C-Fc)

SKU : BHP15200062

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ELK Biotechnology

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Mfr.No.	EPT062
Alternative Names	CD137; ILA; TNFRSF9; 4-1BB ligand receptor; CDw137; T-cell antigen 4-1BB homolog; T-cell antigen ILA
Background	Tumor necrosis factor receptor superfamily member 9(TNFRSF9), also known as CD137 and 4-1BB, is an inducible T cell surface protein belonging to the tumor necrosis factor receptor superfamily. It is a single-pass type I membrane protein which contains 4 TNFR-Cys repeats. The human and mouse proteins share 60% amino acid sequence identity. CD137 is expressed by mesenchymal cells, including endothelial cells, chondrocytes, and cells of the central nervous system. CD137 is also broadly expressed by cells of the human immune system, is broadly expressed by cells of the human immune system, including activated CD8+ and CD4+ T cells, activated natural killer (NK) cells, follicular dendritic cells (FDCs) and monocytes. CD137 has diverse roles in the immune response, the one key function is to promote the survival of both T cells and dendritic cells by binding the cognate ligand CD137L (4-1BBL).
Biological Activity	Immobilized Cynomolgus 4-1BB-Fc(Cat#CB19) at 2ug/ml (100 ul/well)can bind Human 4-1BBL-His-Flag(Cat#C17A). The ED50 of Human 4-1BBL-His-Flag(Cat#C17A)is 0.418 ug/ml.
Description	Recombinant Cynomolgus 4-1BB ligand Receptor is produced by our Mammalian expression system and the target gene encoding Leu24-Gln186 is expressed with a Fc tag at the N-terminus.
Molecular Weight	44.4 KDa
Accession Number	A9YYE7
Endotoxin Level	Less than 0.1 ng/ug (1 EU/ug) as determined by LAL test.
Notes	Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100ug/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Shipping	The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below.
Purity	Greater than 95%
Storage	Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

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SKU	Supplier No.	Size	Your price	Quantity
BHP15200062	EPT062	50ug	$329		Add to Cart

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