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Home / Proteins & Peptide

Recombinant CINC-2α/CXCL3, Rat

SKU : BHP11300154

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Mfr.No.	BK0189‐10μg
Alternative Names	Growth Regulated Protein/Melanoma Growth Stimulatory Activity (MGSA γ) ; CXCL3 ; GRO gamma ; CINC‑2 ; DCIP‑1 ; GRO3
Description	Chemokine (C-X-C motif) ligand 3 (CXCL3) is a small cytokine belonging to the CXC chemokine family that is also known as MIP2β (macrophage inflammatory protein 2 beta), or DCIP1 (dendritic cell inflammatory protein1) in mouse, CINC-2 (cytokineinduced neutrophil attractant 2) in rat, or GROγ (growthregulated oncogene gamma) in human. CXCL3 controls migration and adhesion of monocytes and mediates its effects on target cells by interacting with the cell surface chemokine receptor CXCR2. It has been shown that CXCL3 regulates cerebellar granule neuron precursors toward the internal layers of the cerebellum during cerebellum morphogenesis. CXCL3 is a potential target for medulloblastoma therapy. CXCL3 is regulated transcriptionally by BTG2.Recombinant Rat CINC-2α/CXCL3 produced in CHO cells is a polypeptide chain containing 68 amino acids. A fully biologically active molecule, rrCINC-2α/CXCL3 has a molecular mass of 7.6 kDa analyzed by reducing SDS-PAGE and is obtained by chromatographic techniques at GenScript.
Regulatory	RUO
Source	CHO
Host	Rat
Endotoxin Level	< 0.2 EU/μg, determined by LAL method.
Biological Activity Comment	The EC50 value of rat CINC‑2α/CXCL3 on Caˆ2+ mobilization assay in CHO-K1/Ga15/rCXCR2 cells (human G15 and ratCXCR2 stably expressed in CHO-K1 cells) is less than 100 ng/ml.
Nature	Recombinant

Weight	7.6 kDa, observed by reducing SDS-PAGE.

Description	Reconstituted in ddH2O or PBS at 100 μg/ml.
Format	Lyophilized after extensive dialysis against PBS. Sterile Filtered White lyophilized (freeze-dried) powder.
Purity	> 98% as analyzed by SDS-PAGE.
Storage	Lyophilized recombinant Rat CINC-2α/CXCL3 remains stable up to 6 months at -80°C from date of receipt. Upon reconstitution, recombinant Rat CINC-2α/CXCL3 should be stable up to 1 week at 4°C or up to 2 months at -20°C.

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SKU	Supplier No.	Size	Your price	Quantity
BHP11300154	BK0189‐10μg	10μg	$188.67		Add to Cart
BHP11300154	BK0189‐10μg	1mg	$2055.56		Add to Cart
BHP11300154	BK0189‐10μg	50μg	$423.33		Add to Cart

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