Recombinant 2019-nCoV S2 Protein (C-Fc)

Mfr.No.	EPT188
Description	Recombinant SARS-CoV-2 S2 Protein is produced by our Mammalian expression system and the target gene encoding Ser686-Gln1208 is expressed with a Fc tag at the C-terminus.
Alternative Names	S2 protein; Spike glycoprotein Subunit2; S glycoprotein Subunit2; Spike protein S2; COVID-19
Background	The spike (S) glycoprotein of coronaviruses is known to be essential in the binding of the virus to the host cell at the advent of the infection process. Most notable is severe acute respiratory syndrome (SARS). The severe acute respiratory syndrome-coronavirus (SARS-CoV) spike (S) glycoprotein alone can mediate the membrane fusion required for virus entry and cell fusion. It is also a major immunogen and a target for entry inhibitors. It's been reported that 2019-nCoV can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.
Molecular Weight	84.1kDa
Accession Number	QHD43416.1

Shipping	The product is shipped on dry ice pack.Upon receipt, store it immediately at the temperature listed below.
Purity	Greater than 95%
Storage	Reconstituted protein solution should be stored at <= -20°C.

Have you used this product?

SKU	Supplier No.	Size	Your price	Quantity
BHP15200188	EPT188	1mg	$4439		Add to Cart