Mouse secreted Programmed Cell Death 1 (PD-1)-Fc fusion protein, also known as CD279, PDCD1, and SLEB2, GenBank Accession No. NM_008798, a.a. 25-167, fused at the C-terminus to the Fc portion of mouse IgG2a and with a C-terminal Avi-tag, expressed in a HEK293 cell expression system. This protein was biotinylated using Avi-Tag technology. MW = 45 kDa. Note: this protein runs at an apparent higher molecular weight due to glycosylation.
Immunogen Region
25-167
Tag
C-terminal Fc fusion (Mouse IgG2a), C-terminal Avi-tag
Formulation
8 mM Na Phosphate pH 7.4, 110 mM NaCl, 2.2 mM KCl and 20% glycerol.
Species
Mouse
Application
Useful for the study of protein-protein interaction and in vitro and in vivo protein function studies.
Notes
HiP indicates a high purity protein with>=90% purity as measured by gel filtration. Avoid freeze/thaw cycles.
GenBank
NM_008798
Mw(kda)
45 kDa
Synonyms
Programmed Cell Death 1, CD279, PDCD1, SLEB2
Uniprot
Q02242
Shipping Temperature
-80°C (dry ice)
Storage
At least 6 months at -80°C.
Reference
1. Agata, Y., et al., Internat. Immunol. 1996; 8(5): 765-772.2. Freeman, G.J. et al., J. Exp. Med. 2000; 192(7): 1027-1034.