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Home / Proteins & Peptide

NLRP3 (NALP3) (GKT(231-233)AAA), His-Flag-Tags (HEK293-derived)

SKU : BHP18200906

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BPS Bioscience

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Mfr.No.	100190
Description	Human NLR Family Pyrin Domain Containing 3 (NLRP3), also known as NALP3, Cold Autoinflammatory Syndrome 1 Protein (CIAS1), cryopyrin and PYPAF1 (Genbank Accession No. NM_004895), a.a. 2-1036(end), with N-terminal His-FLAG-tag and with GKTï AAA mutations at 231-233, expressed in a HEK293 expression system. MW = 120 kDa.
Immunogen Region	2-1036 (end)
Tag	N-terminal His-FLAG-tag
Formulation	40 mM Tris-HCl pH 8.0, 110 mM NaCl, 2.2 mM KCl, 10 ng/uL Flag peptide, 3 mM DTT, and 20% glycerol
Species	Human
Notes	Avoid freeze/thaw cycles.
GenBank	NM_004895
Mw(kda)	120 kDa

Synonyms	NLR Family Pyrin Domain Containing 3, NLRP3, Cold Autoinflammatory Syndrome 1 Protein (CIAS1), cryopyrin, PYPAF1, NALP3
Uniprot	Q96P20

Shipping Temperature	-80°C (dry ice)
Format	Aqueous buffer solution
Storage	At least 6 months at -80°C. Protein may be diluted to>= 100 ug/ml in PBS + glycerol and stored at -80°C.

Reference	1. Kummer, J.A., J. Histochem. Cytochem., 2007 May; 55(5):443-52.2. Manji, G.A., J. Biol. Chem. 2002 Mar 29; 277(13):11570-5. Application Reference(s):1. Development of an Acrylate Derivative Targeting the NLRP3 Inflammasome for the Treatment of Inflammatory Bowel Disease (2017)2. BOT-4-one attenuates NLRP3 inflammasome activation: NLRP3 alkylation leading to the regulation of its ATPase activity and ubiquitination (2017)

Product Manual	Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHP18200906	100190	10 ug	$566.50		Add to Cart

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