JavaScript is currently not supported/disabled by this browser. Please enable JavaScript for full functionality.

Call Us 1 - 866 - 986 - 9598
orders@biohippo.com

Sign Up

Login
- My Order
- Return Requests
- Track my Order

Home / Proteins & Peptide

Neurotensin

SKU : BHP21300063

A Ligand of Neurotensin G-Protein Coupled Receptor

Contact us to order

Tel

+1 866.986.9598

Email

orders@biohippo.com

Get a Quote

Request More Infos

Alomone Labs

view supplier details

Order Now

Credit card payments now incur a 3% fee.

Contact us to order

Tel

+1 866.986.9598

Email

orders@biohippo.com

Get a Quote

Ask Merchant

Request More Infos

Sample Request

Mfr.No.	GPN-100, GPN-100_1 mg, GPN-100_10 mg, GPN-100_25 mg, GPN-100_5 mg
Description	A Ligand of Neurotensin G-Protein Coupled Receptor
Reconstitution	Centrifuge the vial (10,000 x g for 5 minutes) before adding solvent to spin down all the powder to the bottom of the vial. The lyophilized product may be difficult to visualize. Add solvent directly to the centrifuged vial. Gently tap, tilt, and roll the vial to aid dissolution. Avoid vigorous vortexing; light vortexing for up to 3 seconds is acceptable if needed. The product is soluble in pure water at high micromolar concentrations (100 uM - 1 mM). For long-term storage in solution, we recommend preparing a stock solution by dissolving the product in double-distilled water (ddH2O) at a concentration between 100-1000x of the final working concentration. Divide the stock solution into small aliquots and store at -20°C. Before use, thaw the relevant vial(s) and dilute to the desired working concentration in your working buffer. Centrifuge all product preparations before use. It is recommended to prepare fresh solutions in working buffers just before use. Avoid multiple freeze-thaw cycles to maintain biological activity.
Molecular Formula	C78H121N21O20
Background	Neurotensin is a peptide neurotransmitter hormone produced from a 170 amino acid precursor protein, first isolated in 1973 from bovine hypothalamus1. Neurotensin signaling is transmitted through three receptors, NTS1 and NTS2 are 7-transmembrane G-protein coupled receptors, and NTS3 is a type I membrane receptor with a large extra cellular domain2.Neurotensin synaptic transmission is terminated primarily by specific enzymatic cleavage of neurotensin by several peptidases3. Neurotensin participates in the regulation of Hypophyseal Prolactin and Luteinizing Hormone (LH) secretion4 and has a pivotal role in the dopaminergic system regulation.Neurotensin is implicated in body temperature regulation, feeding behavior, locomotion regulation5 and pain transmission6.GPCR ligands are now part of our growing portfolio of GPCR related products, which also includes antibodies.
Biological Activity	Neurotensin is an endocrinic or paracrinic hormone. It plays a role in the regulation of fat metabolism, feeding suppression, circadian pacemaker, anti-psychotic-like action, body temperature, dopamine neurotransmission, and smooth muscle contraction and vasodilatation1,2.
Formulation	Lyophilized from double distilled water (ddH2O). May contain TFA as a residual counter ion.
Molecular Weight	1673 Da
Solubility	Centrifuge the vial before adding solvent (10,000 x g for 5 minutes) to spin down all the powder to the bottom of the vial. The lyophilized product may be difficult to visualize. Add solvent directly to the centrifuged vial. Tap the vial to aid in dissolving the lyophilized product. Tilt and gently roll the liquid over the walls of the vial. Avoid vigorous vortexing. Light vortexing for up to 3 seconds is acceptable if needed. The product is soluble in pure water at high micromolar concentrations (100 uM - 1 mM). For long-term storage in solution, we recommend preparing a stock solution by dissolving the product in double-distilled water (ddH2O) at a concentration between 100-1000x of the final working concentration. Divide the stock solution into small aliquots and store at -20°C. Before use, thaw the relevant vial(s) and dilute to the desired working concentration in your working buffer. Centrifuge all product preparations before use. It is recommended to prepare fresh solutions in working buffers just before use. Avoid multiple freeze-thaw cycles to maintain biological activity.
Source	Synthetic peptide
Concentration	5 - 200 nM
Form	Lyophilized
Notes	Bioassay Tested: yes Steril endotoxin free: no Is Toxin: No
Cas Number	55508-42-4
UNSPSC Code	12352202
Lead Time	1-2 Business Days
Modifications	Glu1 - Pyrrolidone carboxylic acid

Synonyms	NTS, NTS1, NT
Gene Id	NTSR1, NTSR2
Sequence	ELYENKPRRPYIL-OH
Target	Neurotensin Receptors

Country Of Origin	Israel/IL
Purity	>=98% (HPLC)
Storage	Storage After Reconstitution: The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods (up to 6 months), small aliquots should be stored at -20°C. We do not recommend storing the product in working solutions for longer than a few days. Avoid multiple freeze-thaw cycles. Storage Before Reconstitution: The product is shipped as a lyophilized powder at room temperature. Upon receipt, store the product at -20°C. Protect from moisture. Storage of solutions: The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods (up to 6 months), small aliquots should be stored at -20°C. We do not recommend storing the product in working solutions for longer than a few days. Avoid multiple freeze-thaw cycles.

Applications	Calcium imaging assay

Reference	Vincent, J.P. et al. (1999) Trends Pharmacol. Sci. 20, 302. Almenoff, J. et al. (1981) Biochem. Biophys. Res. Commun. 102, 206. McCann, S.M. and Vijayan, E. (1992) Annals of the New York Academy of Sciences. 668, 287. Binder, E.B. et al. (2001) Pharmacol. Rev. 53, 453. Maeno, H. et al. (2004) Brain Res. 998, 122. Kislauskis, E. et al. (1988) J. Biol. Chem. 263, 4963. Turner, J.T. et al. (1990) J. Pharmacol. Exp. Ther. 253, 1049. Carraway, R., Leeman, S. E. (1973) J. Biol. Chem. 248, 6854.

Have you used this product?

Rate it now..!!

Login to Review

Combination SKU	Supplier No.	Size	Your price	Quantity
BHP21300063-1	GPN-100_1 mg	1 mg	$45		Add to Cart
BHP21300063-2	GPN-100_10 mg	10 mg	$129		Add to Cart
BHP21300063-3	GPN-100_25 mg	25 mg	$261		Add to Cart
BHP21300063-4	GPN-100_5 mg	5 mg	$91		Add to Cart

ebiohippo.com provides biomedical researchers with a one-stop informatic shopping experience by transforming biotechnology products’ data into a ready-to-analyze state. We collect and unify suppliers’ data on a single platform to reduce the time of searching, uncertainty, and cost of scientific experiments.

© 2025 Biohippo. All rights reserved.