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Home / Proteins & Peptide

NANOG-TAT, Human

SKU : BHP18500204

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iXCells Biotechnologies

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Mfr.No.	IX03001, IX03001-100
Description	NANOG is a transcription factor involved with self-renewal of inner cell mass and embryonic stem (ES) cells by functioning in concert with other factors such as POU5F1 (Oct-4) and SOX2. Nanog imposes pluripotency on ES cells and prevents their differentiation towards extraembryonic endoderm and trophectoderm lineages, and blocks bone morphogenetic protein-induced mesoderm differentiation of ES cells by physically interacting with SMAD1 and interfering with the recruitment of coactivators to the active SMAD transcriptional complexes.Recombinant human NANOG-TAT (rhNANOG-TAT) produced in E. coli is a single chain, 318 amino acids non-glycosylated polypeptide. A fully biologically active molecule, rhNANOG-TAT has a molecular mass of 36.2kDa analyzed by reducing SDS-PAGE and is obtained by proprietary chromatographic techniques.
Formulation	Sterile Filtered solution contains 10mM PB, 300mM NaCl, pH7.4.
Molecular Weight	36.2 kDa, analyzed by reducing SDS-PAGE.
Source	E. coli
Host	Human
Endotoxin Level	0.2 EU/ug, determined by LAL method.
Notes	For research use only

Synonyms	None
Sequence	MSVDPACPQS LPCFEASDCK ESSPMPVICG PEENYPSLQMSSAEMPHTET VSPLPSSMDL LIQDSPDSST SPKGKQPTSAENSVAKKEDK VPVKKQKTRT VFSSTQLCVL NDRFQRQKYLSLQQMQELSN ILNLSYKQVK TWFQNQRMKS KRWQKNNWPKNSNGVTQKAS APTYPSLYSS YHQGCLVNPT GNLPMWSNQTWNNSTWSNQT QNIQSWSNHS WNTQTWCTQS WNNQAWNSPFYNCGEESLQS CMQFQPNSPA SDLEAALEAA GEGLNVIQQTTRYFSTPQTM DLFLNYSMNM QPEDVGGYGR KKRRQRRR

Purity	95% by SDS-PAGE and HPLC analyses.
Storage	Recombinant human NANOG-TAT (rhNANOG-TAT) remains stable up to 1-2 weeks at 4°C from date of receipt. For long term storage, aliquot and store at lower than -70°C. Avoid repeated freezing and thawing cycles.

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Combination SKU	Supplier No.	Size	Your price	Quantity
BHP18500204-1	IX03001-100	100ug	$370		Add to Cart

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