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Home / Proteins & Peptide

Mouse Adiponectin protein, His Tag

SKU : BHP13700095

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Abbkine Scientific Co., Ltd.

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Mfr.No.	PRP100449
Description	Mouse Adiponectin protein, His Tag, expressed in HEK293 Cells
Alternative Names	30kDa; Acdc; Acrp30; Ad; adipo; apM1; APN; GBP28; Adiponectin; ADIPOQ
Background	Adiponectin (ADIPOQ), or 30 kDa adipocyte complement-related protein (Acrp30) is a protein secreted by adipose tissue, which acts to reduce insulin resistance and atherogenic damage, but it also exerts actions in other tissues. Adiponectin mediates its actions in the periphery mainly via two receptors, AdipoR1 and AdipoR2. Adiponectin influences gonadotropin release, normal pregnancy, and assisted reproduction outcomes. Adiponectin, a beneficial adipokine, represents a major link between obesity and reproduction. Higher levels of adiponectin are associated with improved menstrual function and better outcomes in assisted reproductive cycles. Unlike other adipocytokines produced by adipose tissue, adiponectin appears to have anti-inflammatory, anti-diabetic, and anti-atherogenic properties. Several clinical studies demonstrate the inverse relationship between plasma adiponectin levels and several inflammatory markers including C-reactive protein. Adiponectin attenuates inflammatory responses to multiple stimuli by modulating signaling pathways in a variety of cell types. The anti-inflammatory properties of adiponectin may be a major component of its beneficial effects on cardiovascular and metabolic disorders including atherosclerosis and insulin resistance. Additionally, it is important factor in chronic liver diseases and chronic kidney diseases. Some cancer cell types express adiponectin receptors. Thus Adiponectin may act on tumour cells directly by binding and activating adiponectin receptors and downstream signalling pathways.
Immunogen Region	PRP100449
Tag	ADIPOQ
Formulation	Lyophilized from sterile PBS, pH 7.4
Molecular Weight	26.4 kDa
Usage	Always centrifuge tubes before opening. It is recommended to reconstitute the lyophilized Mouse Adiponectin protein, His Tag in sterile ddH2O not less than 100ug/ml, which can then be further diluted to other aqueous solutions.
Accession Number	NP_033735.3
Precautions	The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Protein Length	The secreted recombinant mouse ADIPOQ comprises 241 amino acids and has a calculated molecular mass of 26.4 kDa. As a result of glycosylation, the recombinant protein migrates as an approximately 30 kDa band in SDS-PAGE under reducing conditions.
Others	The Endotoxin level is less than 1.0 EU per ug of the protein as determined by the LAL method Preparation Method: HEK293 Cells

Sequence	Amino acid sequence derived from mouse ADIPOQ (NP_033735.3) (Met 1-Asn 247) was expressed, with a C-terminal polyhistidine tag.

Purity	> 95 % as determined by SDS-PAGE
Storage	Lyophilized Mouse Adiponectin protein, His Tagshould be stored desiccated below -20°C. Upon reconstitution, the protein should be stored at 4°C between 2-7 days and for future use below -20°C. For long term storage it is recommended to add a carrier protein (0.89% HSA or BSA). Please prevent freeze-thaw cycles.

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SKU	Supplier No.	Size	Your price	Quantity
BHP13700095	PRP100449	100 ug	$779		Add to Cart
BHP13700095	PRP100449	1 mg	$4959		Add to Cart

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