Secreted monkey Programmed Cell Death 1 (PD-1)-Fc fusion protein, also known as CD279, PDCD1, and SLEB2, GenBank Accession No. NM_005018, a.a. 25-167, fused at the C-terminus to the Fc portion of human IgG1 with a C-terminal Avitag, expressed in a HEK293 cell expression system. MW = 42.6 kDa. Note: this protein runs at an apparent higher molecular weight due to glycosylation. Biotinylation was confirmed to be>90%.
Immunogen Region
25-167
Tag
C-terminal Fc fusion, C-terminal Avitag
Formulation
8 mM phosphate, pH 7.4, 110 mM NaCl, 2.2 mM KCl, pH 7.4, and 20% glycerol
Species
Monkey
Application
Useful for the study of protein-protein interaction and in vitro and in vivo protein
Notes
The aggregation state of this product has been confirmed to be<10%. Avoid freeze/thaw cycles. Protein may be diluted to>=100 ug/ml in PBS + glycerol and stored at -80°C.
GenBank
NM_001284136.1
Mw(kda)
44.5 kDa
Synonyms
Programmed cell death 1, PDCD1, PD-1, PD1, SLEB2, CD279, HPD-L
Shipping Temperature
-80°C (dry ice)
Format
Aqueous buffer solution
Storage
At least 6 months at -80°C.
Reference
1. Shinohara, T., et al., Genomics. 1994 Oct;23(3):704-6. 2. James, E.S., et al., Genes Immun. 2005 Aug;6(5):430-7.