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Home / Proteins & Peptide

IL-6, His, Mouse

SKU : BHP18500344

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iXCells Biotechnologies

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Mfr.No.	IX03189, IX03189-25, IX03189-5
Description	Interleukin-6 (IL-6), also known as BSF-2, CDF and IFNB2, is a pleiotropic cytokine that participates in both pro-inflammatory and anti-inflammatory responses. It is produced mainly by T cells, macrophages, monocytes, endothelial cells and muscle cells. IL-6 binds to IL-6 receptor (IL-6R) to trigger the association of IL-6R with gp130, inducing signal transduction through JAKs and STATs. The biological functions of IL-6 are diverse. It stimulates B cell differentiation and antibody production, myeloma and plasmacytoma growth, and nerve cell differentiation. It also acts as a myokine, produced by muscle cells in response to muscle contraction and released into the blood stream to help break down fats and improve insulin resistance.
Reconstitution	Reconstituted in ddH2O or PBS at 100 ug/ml.
Formulation	Lyophilized after extensive dialysis against PBS.
Molecular Weight	24-26 kDa, observed by reducing SDS-PAGE.
Source	CHO
Host	Mouse
Accession Number	P08505
Endotoxin Level	0.2 EU/ug, determined by LAL method.
Notes	For research use only
Bioactivity	ED50 3 pg /ml, measured in a bioassay using 7TD1 cells.

Synonyms	26 kDa protein, IFN-b2, B cell differentiation factor (BCDF), BSF-2, HPGF, HSF, MGI-2
Sequence	FPTSQVRRGD FTEDTTPNRP VYTTSQVGGL ITHVLWEIVEMRKELCNGNS DCMNNDDALA ENNLKLPEIQ RNDGCYQTGYNQEICLLKIS SGLLEYHSYL EYMKNNLKDN KKDKARVLQRDTETLIHIFN QEVKDLHKIV LPTPISNALL TDKLESQKEWLRTKTIQFIL KSLEEFLKVT LRSTRQTHHH HHH

Purity	95% as analyzed by SDS-PAGE.
Storage	Lyophilized recombinant murine Interleukin-6 (IL-6), His, Murine remains stable up to 6 months at lower than -70°C from date of receipt. Upon reconstitution, murine Interleukin-6 (IL-6), His should be stable up to 1 week at 4°C or up to 2 months at -20°C.

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Combination SKU	Supplier No.	Size	Your price	Quantity
BHP18500344-1	IX03189-25	25ug	$199		Add to Cart
BHP18500344-2	IX03189-5	5ug	$82		Add to Cart

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