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Home / Proteins & Peptide

IL-19, Human

SKU : BHP18500151

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iXCells Biotechnologies

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Mfr.No.	IX02932, IX02932-1, IX02932-10, IX02932-2
Description	Human Interleukin 19 (IL-19) is a member of the IL-10 family of related cytokines. IL-19 expression has been observed in keratinocytes and monocytes. IL-19 binds a receptor complex consisting of IL-20R alpha and the IL-20 R beta. This receptor complex is also shared by IL-20 and IL-24.
Reconstitution	We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at <= -20 °C. Further dilutions should be made in appropriate buffered solutions.
Formulation	Lyophilized from a 0.2 um filtered concentrated solution in PBS, pH 7.4.
Molecular Weight	Approximately 17.9 kDa, a single non-glycosylated polypeptide chain containing 153 amino acids.
Physical Appearance	Sterile Filtered White lyophilized (freeze-dried) powder.
Source	E. coli
Host	Human
Endotoxin Level	Less than 1 EU/ug of rHuIL-19 as determined by LAL method.
Bioactivity	Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using human IL-20Ralpha and human IL-20Rbeta co-transfected murine BaF3 pro-B cells is less than 1.5 ng/ml, corresponding to a specific activity of 6.7 x 105 IU/mg.

Synonyms	Melanoma differentiation association like protein
Sequence	LRRCLISTDM HHIEESFQEI KRAIQAKDTF PNVTILSTLETLQIIKPLDV?CCVTKNLLAF YVDRVFKDHQ EPNPKILRKI SSIANSFLYMQKTLRQCQEQ?RQCHCRQEAT NATRVIHDNY DQLEVHAAAI KSLGELDVFLAWINKNHEVM?SSA

Purity	95 % by SDS-PAGE and HPLC analyses.
Storage	This lyophilized preparation is stable at 2-8 °C, but should be kept at -20 °C for long term storage, preferably desiccated. Upon reconstitution, the preparation is stable for up to one week at 2-8 °C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20 °C to -70 °C. Avoid repeated freeze/thaw cycles.

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Combination SKU	Supplier No.	Size	Your price	Quantity
BHP18500151-1	IX02932-1	1mg	$4492		Add to Cart
BHP18500151-2	IX02932-10	10ug	$199		Add to Cart
BHP18500151-3	IX02932-2	2ug	$82		Add to Cart

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