Human RSPO1(21-263) Protein, His Tag

Mfr.No.	PME100779
Description	Recombinant human RSPO1(21-263) protein with C-terminal 6×His tag
Background	This gene encodes a secreted actIVator protein with two cysteine-rich, furin-like domains and one thrombospondin type 1 domain. The encoded protein is a ligand for leucine-rich repeat-containing G-protein coupled receptors (LGR proteins) and positIVely regulates the Wnt signaling pathway. In mice, the protein induces the rapid onset of crypt cell proliferation and increases intestinal epithelial healing, proVIding a protectIVe effect against chemotherapy-induced adverse effects. AlternatIVe splicing results in multiple transcript variants. (proVIded by RefSeq, Apr 2014)
Tag	C-6×His tag
Formulation	Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
Molecular Weight	The protein has a predicted molecular mass of 27.6 kDa after removal of the signal peptide. The apparent molecular mass of RSPO1(21-263)-His is approXimately 35-55 kDa due to glycosylation.
Host	HEK293
Notes	Research use only

Purity	The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining.
Storage	Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).

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SKU	Supplier No.	Size	Your price
BHP18100690	PME100779	100 ug	$660	Add to Cart
BHP18100690	PME100779	50 ug	$450	Add to Cart
BHP18100690	PME100779	10 ug	$120	Add to Cart