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Home / Proteins & Peptide

Human PMEL Protein, hFc Tag

SKU : BHP18100345

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DIMA Biotechnology

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Mfr.No.	PME100115
Description	Recombinant human PMEL Protein with C-terminal Human Fc tag
Background	This gene encodes a melanocyte-specific type I transmembrane glycoprotein. The encoded protein is enriched in melanosomes, which are the melanin-producing organelles in melanocytes, and plays an essential role in the structural organization of premelanosomes. This protein is involved in generating internal matriX fibers that define the transition from Stage I to Stage II melanosomes. This protein undergoes a compleX pattern of prosttranslational processing and modification that is essential to the proper functioning of the protein. A secreted form of this protein that is released by proteolytic ectodomain shedding may be used as a melanoma-specific serum marker. Alternate splicing results in multiple transcript variants. (proVIded by RefSeq, Jan 2011)
Tag	C-Human Fc tag
Formulation	Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
Molecular Weight	The protein has a predicted molecular mass of 46.2 kDa after removal of the signal peptide.The apparent molecular mass of PMEL-hFc is approXimately 130-250 kDa due to glycosylation.
Host	HEK293
Notes	Research use only

Synonyms	D12S53E, gp100, ME20, ME20-M, ME20M, P1, P100, PMEL17, SI, SIL, SILV
Uniprot	P40967
Target	PMEL

Purity	The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining.
Storage	Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).

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SKU	Supplier No.	Size	Your price	Quantity
BHP18100345	PME100115	100 ug	$400		Add to Cart
BHP18100345	PME100115	50 ug	$270		Add to Cart
BHP18100345	PME100115	10 ug	$70		Add to Cart

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