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Home / Proteins & Peptide

Human MUC1 Protein, HisTag

SKU : BHP18100329

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DIMA Biotechnology

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Mfr.No.	PME100106
Description	Recombinant Human MUC1 Protein with C-terminal 6×His tag
Background	This gene encodes a membrane-bound protein that is a member of the mucin family. Mucins are O-glycosylated proteins that play an essential role in forming protectIVe mucous barriers on epithelial surfaces. These proteins also play a role in intracellular signaling. This protein is eXpressed on the apical surface of epithelial cells that line the mucosal surfaces of many different tissues including lung, breast stomach and pancreas. This protein is proteolytically cleaved into alpha and beta subunits that form a heterodimeric compleX. The N-terminal alpha subunit functions in cell-adhesion and the C-terminal beta subunit is involved in cell signaling. OvereXpression, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with carcinomas. This gene is known to contain a highly polymorphic variable number tandem repeats (VNTR) domain. Alternate splicing results in multiple transcript variants.
Tag	C-6×His tag
Formulation	Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
Molecular Weight	The protein has a predicted molecular mass of 14.4 kDa after removal of the signal peptide.
Host	HEK293
Notes	Research use only

Synonyms	ADMCKD, ADMCKD1, CA 15-3, CD227, EMA, H23AG, KL-6, MAM6, MCD, MCKD, MCKD1, MUC-1, MUC-1/SEC, MUC-1/X, MUC1/ZD, PEM, PEMT, PUM
Uniprot	P15941
Target	MUC1

Purity	The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining.
Storage	Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).

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SKU	Supplier No.	Size	Your price	Quantity
BHP18100329	PME100106	100 ug	$380		Add to Cart
BHP18100329	PME100106	50 ug	$260		Add to Cart
BHP18100329	PME100106	10 ug	$65		Add to Cart

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