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Home / Proteins & Peptide

Human H3F3A / Histone H3.3 Recombinant Protein

SKU : BHP13800132

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	R5810h
Alternative Names	H3.3A,H3F3,PP781
Source	E.coli
Species	Homo Sapiens (Human)
Accession Number	P84243
Endotoxin Level	<0.10 EU per 1 μg of the protein by the LAL method
Concentration	Reconstitution Dependent
Form	Liquid
Protein Name	Histone H3.3
Entry Function	Variant histone H3 which replaces conventional H3 in a wide range of nucleosomes in active genes. Constitutes the predominant form of histone H3 in non-dividing cells and is incorporated into chromatin independently of DNA synthesis. Deposited at sites of nucleosomal displacement throughout transcribed genes, suggesting that it represents an epigenetic imprint of transcriptionally active chromatin. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Mw(kda)	8.91

Subunit	The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. Interacts with HIRA, a chaperone required for its incorporation into nucleosomes. Interacts with ZMYND11; when trimethylated at 'Lys-36' (H3.3K36me3).
Gene Name	H3F3A
Sequence	1-81aa

Purity	Greater than 95% by SDS-PAGE
Storage	Store at -20°C. (Avoid repeated freezing and thawing.)
Storage Buffer	50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole,10%glycerol(PH8.0)

Applications	Par, ELISA, AP, WB

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SKU	Supplier No.	Size	Your price	Quantity
BHP13800132	R5810h	50µg	$637.78		Add to Cart
BHP13800132	R5810h	100µg	$904.44		Add to Cart
BHP13800132	R5810h	200µg	$1348.89		Add to Cart
BHP13800132	R5810h	0.5mg	$1971.11		Add to Cart
BHP13800132	R5810h	1mg	$2682.22		Add to Cart
BHP13800132	R5810h	5mg	$4637.78		Add to Cart
BHP13800132	R5810h	10mg	$6148.89		Add to Cart

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