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Home / Proteins & Peptide

Human CDKN2A / Cyclin-dependent kinase inhibitor 2A, isoforms 1/2/3 Recombinant Protein

SKU : BHP13800066

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	R0794h
Alternative Names	Cyclin-dependent kinase 4 inhibitor A,CDK4I,Multiple tumor suppressor 1,MTS-1,p16-INK4a,p16-INK4,p16INK4A,CDKN2,MTS1
Source	E.coli
Species	Homo Sapiens (Human)
Accession Number	P42771
Endotoxin Level	<0.10 EU per 1 μg of the protein by the LAL method
Concentration	Reconstitution Dependent
Form	Liquid
Protein Name	Cyclin-dependent kinase inhibitor 2A, isoforms 1/2/3
Entry Function	Acts as a negative regulator of the proliferation of normal cells by interacting strongly with CDK4 and CDK6. This inhibits their ability to interact with cyclins D and to phosphorylate the retinoblastoma protein.
Mw(kda)	9.68

Subunit	Heterodimer with CDK4 or CDK6. Predominant p16 complexes contained CDK6. Interacts (isoforms 1,2 and 4) with CDK4 (both 'T-172'-phosphorylated and non-phosphorylated forms); the interaction inhibits cyclin D-CDK4 kinase activity. Interacts with ISCO2.
Gene Name	CDKN2A
Sequence	69-156aa

Purity	Greater than 95% by SDS-PAGE
Storage	Store at -20°C. (Avoid repeated freezing and thawing.)
Storage Buffer	50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole,10%glycerol(PH8.0)

Applications	Par, ELISA, AP, WB

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SKU	Supplier No.	Size	Your price	Quantity
BHP13800066	R0794h	50µg	$637.78		Add to Cart
BHP13800066	R0794h	100µg	$904.44		Add to Cart
BHP13800066	R0794h	200µg	$1348.89		Add to Cart
BHP13800066	R0794h	0.5mg	$1971.11		Add to Cart
BHP13800066	R0794h	1mg	$2682.22		Add to Cart
BHP13800066	R0794h	5mg	$4637.78		Add to Cart
BHP13800066	R0794h	10mg	$6148.89		Add to Cart

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