Human CALR Protein, hFc Tag

Mfr.No.	PME100916
Description	Recombinant human CALR protein with C-terminal human Fc tag
Background	Calreticulin is a highly conserved chaperone protein which resides primarily in the endoplasmic reticulum, and is involved in a variety of cellular processes, among them, cell adhesion. Additionally, it functions in protein folding quality control and calcium homeostasis. Calreticulin is also found in the nucleus, suggesting that it may have a role in transcription regulation. Systemic lupus erythematosus is associated with increased autoantibody titers against calreticulin. Recurrent mutations in calreticulin have been linked to various neoplasms, including the myeloproliferatIVe type.(proVIded by RefSeq, May 2020)
Tag	C-Human Fc
Formulation	Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
Molecular Weight	The protein has a predicted molecular mass of 79.53 kDa after removal of the signal peptide.
Host	HEK293
Notes	Research use only

Purity	The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining.
Storage	Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).

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SKU	Supplier No.	Size	Your price
BHP18100218	PME100916	100 ug	$360	Add to Cart
BHP18100218	PME100916	50 ug	$240	Add to Cart
BHP18100218	PME100916	10 ug	$60	Add to Cart