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Home / Proteins & Peptide

HSP70, His-tag

SKU : BHP18200380

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BPS Bioscience

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Mfr.No.	50287
Description	Human Heat Shock Protein 70 (GenBank Accession No. NM_005345), a.a. 2-641 with C-terminal His-tag, MW = 71 kDa, expressed in E. coli.
Background	In cooperation with other chaperones, Hsp70 stabilizes preexistent proteins against aggregation and mediate the folding of newly translated polypeptides in the cytosol as well as within organelles. These chaperones participate in all these processes through their ability to recognize nonnative conformations of other proteins. They bind extended peptide segments with a net hydrophobic character exposed by polypeptides during translation and membrane translocation, or following stress-induced damage.
Immunogen Region	2-641
Tag	C-terminal His-tag
Formulation	40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCl, 3 mM DTT, 20% glycerol, and 200 mM imidazole
Species	Human
Application	Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling
Notes	Avoid freeze/thaw cycles.
GenBank	NM_005345
Mw(kda)	71 kDa

Synonyms	HSP70, Heat Shock Protein 70, DnaK, HSP70i
Uniprot	P08107

Shipping Temperature	-80°C (dry ice)
Format	Aqueous buffer solution
Storage	At least 6 months at -80°C.

Reference	1. Lee K.J. et al., Exp. Mol. Med. 40 (6), 658-668 (2008). 2. Birtas-Atesoglu E. et al., Clin. Exp. Rheumatol. 26, S96-S98 (2008).

Product Manual	Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHP18200380	50287	200 ug	$423.50		Add to Cart

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