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HDAC2, His-tag

BHP18200302
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Tel
+1 866.986.9598
Email
orders@biohippo.com
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Synonyms histone deacetylase 2, HDAC-2
Uniprot Q92769
Shipping Temperature -80°C (dry ice)
Format Aqueous buffer solution
Storage At least 6 months at -80°C.
Reference 1. Yang,W.M. et al., Proc. Natl. Acad. Sci. U.S.A. 93 (23), 12845-12850 (1996).
2. Mungall, A.J. et al., Nature 425 (6960), 805-811 (2003).Application References:
1. Jang, S., et al. Cancer Gene Ther. 2015 Aug;22(8):410-6. doi: 10.1038/cgt.2015.37. Novel analogs targeting histone deacetylase suppress aggressive thyroid cancer cell growth and induce re-differentiation (2015)
2. Wang, Y., et al. Chem Biol. 2015 Feb 19;22(2):273-84. doi: 10.1016/j.chembiol.2014.12.015. Identification of histone deacetylase inhibitors with benzoylhydrazide scaffold that selectively inhibit class I histone deacetylases (2015)
3.Tumor-suppressor role of Notch3 in medullary thyroid carcinoma revealed by genetic and pharmacological induction (2015)
4.A chimeric SERM-histone deacetylase inhibitor approach to breast cancer therapy (2014)
5.Design, synthesis, 3D pharmacophore, QSAR, and docking studies of carboxylic acid derivatives as Histone Deacetylase inhibitors and cytotoxic agents (2014)
6.Discovery of a small molecule agonist of phosphatidylinositol 3-kinase p110alpha that reactivates latent HIV-1 (2014)
7. Wang, C., et al. J Med Chem. 2014 Oct 9;57(19):7999-8009. doi: 10.1021/jm500872p. In Vivo Imaging of Histone Deacetylases (HDACs) in the Central Nervous System and Major Peripheral Organs (2014)
8.Reassessing the effects of histone deacetylase inhibitors on hippocampal memory and cognitive aging (2014)
9.The effect of various zinc binding groups on inhibition of histone deacetylases 1-11 (2014)
10.Selective HDAC Inhibition for the Disruption of Latent HIV-1 Infection (2014)
11.Class I HDAC imaging using ( (3)H)CI-994 autoradiography (2013)
12.A selective HDAC 1/2 inhibitor modulates chromatin and gene expression in brain and alters mouse behavior in two mood-related tests (2013)
13.Fass, D.M., et al. Neuropharmacology. 2013 Jan; 64: 81–96. Crebinostat: a novel cognitive enhancer that inhibits histone deacetylase activity and modulates chromatin-mediated neuroplasticity (2013)
14.FDG-PET imaging reveals local brain glucose utilization is altered by class I histone deacetylase inhibitors (2013)
15. Baud, MGJ, et al. ChemMedChem. 2013 Jan;8(1):149-56. doi: 10.1002/cmdc.201200450. Highly ligand efficient and selective N-2-(Thioethyl)picolinamide histone deacetylase inhibitors inspired by the natural product psammaplin A (2013)
16.Imaging epigenetic regulation by histone deacetylases in the brain using PET/MRI with ¹¸F-FAHA (2013)
Pavlik, C.M., et al. J Nat Prod. 2013 Nov 22;76(11):2026-33. doi: 10.1021/np400198r. Santacruzamate A, a potent and selective histone deacetylase inhibitor from the Panamanian marine cyanobacterium cf. Symploca sp (2013)
18.Total synthesis and full histone deacetylase inhibitory profiling of Azumamides A-E as well as beta²- epi-Azumamide E and beta³-epi-Azumamide E (2013)
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BHP18200302 50002 50 ug $522.50
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