Mouse secreted Cytotoxic T-lymphocyte-associated protein 4 (CTLA4), also known as CD152, GenBank Accession No. NM_009843, a.a. 36-161 fused at the C-terminus with the Fc portion of human IgG1 and a C-terminal Avi-Tag, expressed in a HEK293 cell expression system. MW = 42 kDa. This protein runs at a higher MW by SDS-PAGE due to glycosylation.
Immunogen Region
36-161
Tag
Avi-Tag
Formulation
8 mM phosphate, pH 7.4, 110 mM NaCl, 2.2 mM KCl, and 20% glycerol.
Species
Mouse
Application
Useful for the study of protein-protein interaction and in vitro and in vivo protein function.
Notes
The aggregation state of this product has been confirmed to be<10%. Avoid freeze/thaw cycles.
GenBank
NM_009843
Mw(kda)
42 kDa
Synonyms
Cytotoxic T-lymphocyte-associated protein 4, CD152,
Uniprot
P09793
Shipping Temperature
-80°C (dry ice)
Format
Aqueous buffer solution
Storage
Stable at least 6 months at -80°C. Protein may be diluted to>= 100 ug/ml in PBS + glycerol and stored at -80°C.
Reference
1. Dilek, N., et al., PLoS ONE. 2013; 8(12): e83139. 2. Leach, D.R., et al., Science. 1996; 271(5256):1734-1736.