Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negatively regulates the kinase activity of PDPK1.
Categories
Primary Antibodies
Clonality
polyclonal
Description
Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negatively regulates the kinase activity of PDPK1.
Host
Rabbit
Immunogen
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide
Isotype
IgG
Molecular Weight
28 kDa
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Synonyms
14 3 3 protein eta, 14-3-3, 14-3-3 eta, Protein AS1, YWHA1, YWHAH
Uniprot
Q04917
Gene Id
7533
Research Area
Signal Transduction, Metabolism
Weight
28kDa
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)