Regulates actin polymerization by stimulating the actin-nucleating activity of the Arp2/3 complex. Involved in mitosis and cytokinesis, via its role in the regulation of actin polymerization. Binds to HSF1/HSTF1 and forms a complex on heat shock promoter elements(HSE) that negatively regulates HSP90 expression.
Categories
Primary Antibodies
Clonality
polyclonal
Description
Regulates actin polymerization by stimulating the actin- nucleating activity of the Arp2/3 complex. Involved in mitosis and cytokinesis, via its role in the regulation of actin polymerization. Binds to HSF1/HSTF1 and forms a complex on heat shock promoter elements (HSE) that negatively regulates HSP90 expression.
Host
Rabbit
Immunogen
Wiskott-Aldrich syndrome-like
Isotype
IgG
Molecular Weight
55 kDa
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Synonyms
DKFZp779G0847, N WASP, NWASP, WASL, Wiskott Aldrich syndrome like
Uniprot
O00401
Gene Id
8976
Research Area
cancer, Metabolism, Neuroscience
Weight
55kDa
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)