This gene is a member of the sauvagine/corticotropin-releasing factor/urotensin I family. It is structurally related to the corticotropin-releasing factor (CRF) gene and the encoded product is an endogenous ligand for CRF type 2 receptors. In the brain it may be responsible for the effects of stress on appetite. In spite of the gene family name similarity, the product of this gene has no sequence similarity to urotensin II.
Categories
Primary Antibodies
Cellular Localization
Secreted
Clonality
polyclonal
Description
Suppresses food intake, delays gastric emptying and decreases heat-induced edema. Might represent an endogenous ligand for maintaining homeostasis after stress.
Host
Rabbit
Immunogen
urocortin 2
Isotype
IgG
Molecular Weight
12 kDa
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Subcellular Location
Secreted
Synonyms
SRP, Stresscopin related peptide, UCN II, UCN2, UCNI, UR, urocortin 2, Urocortin II, Urocortin related peptide, URP
Uniprot
Q96RP3
Gene Id
90226
Research Area
Signal Transduction, Metabolism
Weight
12kDa
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)