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Home / Primary Antibodies / Polyclonal Antibodies

TFDP1 antibody

SKU : BHA10808616

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Mfr.No.	FNab08624
Alternative Names	DP1
Background	This gene encodes a member of a family of transcription factors that heterodimerize with E2F proteins to enhance their DNA-binding activity and promote transcription from E2F target genes. The encoded protein functions as part of this complex to control the transcriptional activity of numerous genes involved in cell cycle progression from G1 to S phase. Alteative splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 1, 15, and X.
Categories	Primary Antibodies
Clonality	polyclonal
Description	Can stimulate E2F-dependent transcription. Binds DNA cooperatively with E2F family members through the E2 recognition site, 5'-TTTC[CG]CGC-3', found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The E2F1:DP complex appears to mediate both cell proliferation and apoptosis. Blocks adipocyte differentiation by repressing CEBPA binding to its target gene promoters (PubMed:20176812).
Host	Rabbit
Immunogen	transcription factor Dp-1
Isotype	IgG
Molecular Weight	45 kDa
Reactivity	Human, Mouse
Regulatory	RUO
Synonyms	DP1

Uniprot	Q14186
Gene Id	7027
Research Area	Cell Division and Proliferation, Metabolism

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Applications	ELISA, IHC
Description	ELISA ; IHC
Tested Application	WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

Manual	FNab08624.pdf

No Description Available.

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SKU	Supplier No.	Size	Your price	Quantity
BHA10808616	FNab08624	100ug	$300		Add to Cart

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