T-cell acute lymphocytic leukemia protein 1 (TAL1) also named Stem cell protein,T-cell leukemia/lymphoma protein 5.It is specifically expressed in leukemic stem cell,implicated in the genesis of hemopoietic malignancies. It may play an important role in hemopoietic differentiation, serving as a positive regulator of erythroid differentiation. The 38kd, 44kd bands recognized by antibody are the phosphorylated forms of TAL1 and it's isoforms.
Clonality
polyclonal
Host
Rabbit
Immunogen
T-cell acute lymphocytic leukemia 1
Immunogen Region
T-cell acute lymphocytic leukemia 1
Isotype
IgG
Molecular Weight
38,44 kDa
Reactivity
Human
Recommended Dilution
WB: 1:200-1:2000
Synonyms
bHLHa17, SCL, Stem cell protein, tal 1, TAL1, TCL5
Uniprot
P17542
Gene Id
6886
Research Area
Epigenetics, Developmental biology, Metabolism, Cardiovascular, Cancer
Form
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)
Tested Application
WB: 1:200-1:2000
Product Manual
<a href="https://www.fn-test.com/content/uploads/product/manuals/antibody/FNab10041.pdf" target="_blank">Data Sheet</ a>