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Home / Primary Antibodies / Polyclonal Antibodies

SQLE antibody

SKU : BHA10808201

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Mfr.No.	FNab08209
Alternative Names	ERG1 ; FLJ30795 ; SE ; SM ; SQLE ; squaleneepoxidase ; Squalenemonooxygenase
Background	SQLE, also named as ERG1, SE and SM, belongs to the squalene monooxygenase family. It catalyzes the first oxygenation step in cholesterol synthesis, acting on squalene before cyclization into the basic steroid structure. SQLE may serve as a flux-controlling enzyme beyond 3-hydroxy-3-methylglutaryl-coenzyme A reductase(HMGR, considered as rate limiting). It is also posttranslationally regulated by cholesterol-dependent proteasomal degradation.(PMID:21356516) The MW of SQLE is about 64kd.
Categories	Primary Antibodies
Clonality	polyclonal
Description	SQLE, also named as ERG1, SE and SM, belongs to the squalene monooxygenase family. It catalyzes the first oxygenation step in cholesterol synthesis, acting on squalene before cyclization into the basic steroid structure. SQLE may serve as a flux-controlling enzyme beyond 3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMGR, considered as rate limiting). It is also posttranslationally regulated by cholesterol-dependent proteasomal degradation.(PMID:21356516) The MW of SQLE is about 64kd.
Host	Rabbit
Immunogen	squalene epoxidase
Isotype	IgG
Molecular Weight	64 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Synonyms	ERG1, FLJ30795, SE, SM, SQLE, squalene epoxidase, Squalene monooxygenase

Uniprot	Q14534
Gene Id	6713
Research Area	Metabolism
Weight	64 kDa

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications

ELISA, WB, IHC, IP, IF

Description

ELISA ; WB ; IHC ; IP ; IF

Dilution

WB	1:200-1:2000

Tested Application

WB: 1:200-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200; IF: 1:20-1:200

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SKU	Supplier No.	Size	Your price	Quantity
BHA10808201	FNab08209	100ug	$300		Add to Cart

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