This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. The encoded protein may play a role in chondrogenesis. A pseudogene of this gene is located on chromosome 8. Multiple transcript variants encoding distinct isoforms have been identified for this gene.
Categories
Primary Antibodies
Clonality
polyclonal
Description
Binds specifically to the DNA sequence 5'-AACAAT-3'. Activates transcription of COL2A1 and AGC1 in vitro.
Host
Rabbit
Immunogen
SRY (sex determining region Y)-box 5
Isotype
IgG
Molecular Weight
70 kDa
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Uniprot
P35711
Gene Id
6660
Research Area
Epigenetics, Stem Cells, Metabolism, Neuroscience
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)