The protein encoded by this gene is an evolutionarily conserved protein similar to yeast SSF1 as well as to the gene product of the Drosophila gene peter pan (ppan). SSF1 is known to be involved in the second step of mRNA splicing. Both SSF1 and ppan are essential for cell growth and proliferation. Exogenous expression of this gene was reported to reduce the anchorage-independent growth of some tumor cells. Read-through transcription of this gene with P2RY11/P2Y(11), an adjacent downstream gene that encodes an ATP receptor, has been found. These read-through transcripts are ubiquitously present and up-regulated during granulocyte differentiation.
Categories
Primary Antibodies
Clonality
polyclonal
Description
May have a role in cell growth.
Host
Rabbit
Immunogen
peter pan homolog (Drosophila)
Isotype
IgG
Molecular Weight
55 kDa
Reactivity
Human, Mouse
Regulatory
RUO
Synonyms
BXDC3, SSF1
Uniprot
Q9NQ55
Gene Id
56342
Research Area
Metabolism
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)