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Home / Primary Antibodies / Polyclonal Antibodies

PLS3 antibody

SKU : BHA10806550

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Mfr.No.	FNab06558
Background	Plastins are a family of actin-binding proteins that are conserved throughout eukaryote evolution and expressed in most tissues of higher eukaryotes. In humans, two ubiquitous plastin isoforms (L and T) have been identified. Plastin 1 (otherwise known as Fimbrin) is a third distinct plastin isoform which is specifically expressed at high levels in the small intestine. The L isoform is expressed only in hemopoietic cell lineages, while the T isoform has been found in all other normal cells of solid tissues that have replicative potential (fibroblasts, endothelial cells, epithelial cells, melanocytes, etc.). The C-terminal 570 amino acids of the T-plastin and L-plastin proteins are 83% identical. It contains a potential calcium-binding site near the N terminus. Alteate splicing results in multiple transcript variants.
Categories	Primary Antibodies
Clonality	polyclonal
Description	Actin-bundling protein found in intestinal microvilli, hair cell stereocilia, and fibroblast filopodia. May play a role in the regulation of bone development.
Host	Rabbit
Immunogen	plastin 3 (T isoform)
Isotype	IgG
Molecular Weight	71 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO

Antigen	PLS3
Uniprot	P13797
Gene Id	5358
Research Area	Signal Transduction

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB
Description	ELISA ; WB
Tested Application	WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200

Manual	FNab06558.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10806550	FNab06558	100ug	$300		Add to Cart

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