The protein encoded by this gene catalyzes the hydrolysis of phosphatidylcholine to phosphatidic acid and choline. The activity of the encoded enzyme is enhanced by phosphatidylinositol 4,5-bisphosphate and ADP-ribosylation factor-1. This protein localizes to the peripheral membrane and may be involved in cytoskeletal organization, cell cycle control, transcriptional regulation, and/or regulated secretion. Two transcript variants encoding different isoforms have been found for this gene.
Clonality
polyclonal
Host
Rabbit
Immunogen
PLD2
Immunogen Region
PLD2
Isotype
IgG
Molecular Weight
110 kDa
Reactivity
Human, Rat
Recommended Dilution
IHC: 1:20-1:200
Synonyms
PLD2, PLD1C, phospholipase D2
Uniprot
O14939
Gene Id
5338
Research Area
Cardiovascular, Signal Transduction, Metabolism
Form
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)
Tested Application
IHC: 1:20-1:200
Product Manual
<a href="https://www.fn-test.com/content/uploads/product/manuals/antibody/FNab10085.pdf" target="_blank">Data Sheet</ a>